Sheba Pediatric CAR-T Program for Burkitt Lymphoma

• Thérapie CAR T
• Test anti-VIH
• Test anti-HBC
• Test anti-VHCAb
• Des analyses de sang
• Test sanguin de biochimie
• Biopsie
• Radiographie pulmonaire
• Formule sanguine complète (CBC)
• Consultation avec un oncologue
• Consultation avec un hématologue
• Consultation avec un immunologiste
• Consultation avec un cardiologue
• Consultation avec un hématologue pédiatrique
• Consultation avec un pédiatre
• Formule sanguine complète avec marqueurs de cancer et protéinogramme
• Électrocardiogramme
• Échocardiographie
• IRM de la tête
• Сonsultation avec un oncohématologue
• Service infirmier 24h/24
• 3 repas par jour élaborés par un nutritionniste

• 20 jours à l'hôpital

• Transfert aéroport-clinique-aéroport

Sheba Pediatric CAR-T Program for Burkitt Lymphoma

At Sheba Medical Center, children and young patients with Burkitt lymphoma have access to one of the most advanced and trusted CAR-T therapy programs in the world. This highly aggressive form of lymphoma requires rapid, precise treatment, especially in relapsed or treatment-resistant cases where CAR-T therapy offers a powerful, personalized option.

A Personalized Treatment Designed for Each Child

CAR-T therapy uses the patient’s own immune system to recognize and eliminate cancer cells. For children with Burkitt lymphoma, this innovative approach can provide new hope when conventional therapies are no longer effective.

At Sheba, the entire CAR-T process is performed on-site, ensuring speed, precision, and optimal cell quality:

Apheresis – collection of the patient’s T-cells
Cell Engineering – genetic modification at Sheba’s Advanced Biotherapy Center
Infusion – reintroduction of modified cells to target lymphoma

Because no steps are outsourced, treatment can begin quickly and is typically completed within ~10 days. CAR-T acts as a “living therapy,” continuing to work in the body and offering the potential for durable remission.

Expert Pediatric Leadership and Care

The program is led by Prof. Amos Toren, a world-recognized expert in pediatric hemato-oncology and cellular therapies, with decades of experience and more than 1,500 bone marrow transplants performed.

Children are cared for within a dedicated pediatric environment that includes:

Specialized pediatric CAR-T units with 24/7 monitoring
A multidisciplinary team of experts in hematology, oncology, and immunology
A family-centered approach, focused on comfort, safety, and support
Full international patient services, including travel and care coordination
Proven Expertise in Complex Cases

Sheba is a global leader in pediatric CAR-T therapy, with strong clinical outcomes:

~90% remission in pediatric patients
~80% in young adults (up to 23 years)
~70% in adults

The team has extensive experience treating high-risk and aggressive lymphomas, including Burkitt lymphoma, offering advanced options when other treatments have limited success.

Comprehensive Evaluation and Support

Each child undergoes a full diagnostic work-up before treatment, including:
advanced imaging, bone marrow evaluation, genetic and molecular testing, and cardiac and pulmonary assessment.

Care is provided in English, Russian, and Arabic, ensuring families feel supported and informed throughout the entire process.

A Trusted Place for Advanced Pediatric Cancer Care

By combining rapid access to treatment, leading medical expertise, and compassionate pediatric care, Sheba provides one of the most trusted environments for treating Burkitt lymphoma with CAR-T therapy focused on achieving remission and helping children return to a healthy and active life.

• Coordinateur médical personnel
• Organisation de voyage médical — réservation des tickets de vol et des chambres d'hôtel à des prix réduits pour les partenaires
• Prise en charge du patient lors d'un voyage médical