Les Meilleurs doctors - TOP-142 des médecins

Le Dr Cem Altındağ est un chirurgien consultant en oto-rhino-laryngologie et chirurgie de la tête et du cou diplômé de l'Université d'Istanbul en 1989. Il a effectué plusieurs stages d'observation, consultations honoraires, cours et réunions dans divers pays tels que les États-Unis, l'Autriche, l'Allemagne, le Royaume-Uni, le Portugal, Pays-Bas, Italie et France. Il est également membre de la Société Européenne de Rhinoplastie.

Le Dr. est titulaire d'une maîtrise en gestion des hôpitaux et des établissements de santé et a travaillé dans de nombreuses institutions, telles que l'hôpital de formation et de recherche Haseki du ministère de la Santé et l'université Bezmialem. Il a participé à de nombreuses conférences internationales et remporté des prix, et a publié des articles de recherche. Ses domaines d'expertise comprennent l'esthétique du nez, l'implant cochléaire, les pertes auditives, les infections de l'oreille, les troubles de l'équilibre, les allergies nasales, la polypose nasale, la chirurgie du cancer, la chirurgie plastique faciale, les troubles de la voix, les nodules thyroïdiens, la sinusite, la chirurgie endoscopique des sinus, les maladies des amygdales et des végétations adénoïdes et le ronflement, la chirurgie de l'apnée du sommeil. Il a acquis une expérience internationale aux États-Unis à l'université Johns Hopkins, à l'université Harvard, à la faculté de médecine de Harvard, à l'hôpital pour enfants de Boston, à l'université Tufts et à la Cleveland Clinic.

Dr. Ibrahim Altoparlak is an experienced ENT specialist with more than 13 years in clinical practice. He focuses on advanced otolaryngology and facial aesthetic procedures. Dr. Altoparlak is skilled in Rhinoplasty, Revision Rhinoplasty, Rhinoseptoplasty, and Ear Reconstruction. He has performed hundreds of surgeries with a strong record of patient satisfaction.

He completed his medical degree and ENT specialization at Ankara University, one of Turkey’s top institutions. Dr. Altoparlak holds recognized accreditations in otolaryngology. He continues to advance his field through ongoing professional development and new surgical methods. His practice is known for high standards in both functional and cosmetic ENT surgery.

Prof. Dr. Salim Yuce is an experienced ENT surgeon with over 28 years in the field. He specializes in procedures such as tympanoplasty, cochlear implants, and nasal polyp surgery. Dr. Yuce has performed many successful surgeries, earning high patient satisfaction and strong surgical outcomes.

He graduated from Istanbul University and completed his residency at Haseki Training and Research Hospital. Dr. Yuce is a member of the European Rhinologic Society and the American College of Surgeons. He is dedicated to professional growth and high standards in patient care.

Dr. Emre Gunbey is an Assistant Professor of ENT. He specializes in nose aesthetics, endoscopic sinus surgery, snoring and sleep apnea, and head and neck tumor surgery. He graduated from Ege University School of Medicine in 2003. He completed his ENT residency at Kecioren Training and Research Hospital in 2011.

Dr. Gunbey has worked at Lokman Hekim Istanbul Hospital and Adatip Istanbul Hospital. He also gained international experience as an observer at Mayo Clinic in the USA. He is a member of the European Board of Otorhinolaryngology and Head and Neck Surgery, the European Rhinology Association, and the Facial Plastic Surgery Association.

Dr. Mustafa Akarcay is an experienced ENT specialist with over 20 years in otolaryngology. He is known for his advanced treatments and surgical skills in ear, nose, and throat diseases.

He has led the ENT Department at Demiroğlu Bilim University Faculty of Medicine – Şişli Florence Nightingale Hospital. He also served as Associate Professor at İzmir and İnönü Universities. Dr. Akarcay has made important contributions to research and education in his field.

He has worked at leading Turkish hospitals, including Memorial Şişli Hospital, Medistate Kavacık Hospital, and Şişli Kolan International Hospital. There, he used innovative ENT techniques and mentored new specialists.

Assoc. Prof. Selman Sarica, M.D., is a board-certified otorhinolaryngologist. He specializes in otology, pediatric ENT, snoring surgery, head and neck tumors, laryngology, functional nasal surgery, endoscopic sinus surgery, thyroid surgery, and salivary gland surgery. He received his medical degree from Istanbul University Cerrahpaşa Faculty of Medicine. He completed his ENT residency at Kahramanmaraş Sütçü İmam University, where he now serves as an Associate Professor.

Dr. Sarica has performed hundreds of advanced ear, nose, and throat surgeries. His experience includes complex head and neck tumor resections and endoscopic procedures. He is known for his research in voice analysis and has published several peer-reviewed articles. Dr. Sarica holds national accreditation and is respected for his clinical and academic work in ENT.

Prof. Dr. Tayfun Apuhan is a specialist in ENT and Head & Neck Surgery. He is known for his skill in treating ear infections, repairing the tympanic membrane, and performing rhinoplasty and septorhinoplasty. He also has experience in adenoidectomy, tonsillectomy, sleep apnea surgery, vocal cord microsurgery, and head and neck tumor surgery. Dr. Apuhan founded the ENT and Head & Neck Surgery Department at Özel A Plus Hisar Intercontinental Hospital.

Dr. Apuhan earned his medical degree from İnönü University. He completed further training at Abant Izzet Baysal University, University Medical Center Hamburg-Eppendorf, Gazi University, and The Ohio State University Comprehensive Cancer Center. He has published over 200 scientific articles. He has also served as a session chair and editor at international conferences and journals. Dr. Apuhan currently leads the audiometry program at Doğuş University.

Igor Anurin est un médecin spécialiste (selon le système de qualification des médecins en Pologne et dans l'Union européenne), médecin de la plus haute catégorie, fort de dix-sept ans d'expérience dans des cliniques renommées de Varsovie. Il est spécialisé en chirurgie endoscopique des sinus, redressement de la cloison nasale, rhinoplastie, chirurgie plastique du voile du palais (traitement du ronflement et de l'apnée du sommeil), tumeurs des glandes salivaires, traitement et diagnostic des cancers de la tête et du cou, ainsi qu'en prise en charge ambulatoire des maladies aiguës et chroniques des voies respiratoires supérieures. Le Dr Anurin est également membre de la Société polonaise d'oto-rhino-laryngologie et de chirurgie cervico-faciale. Il participe régulièrement à des congrès scientifiques et pratiques internationaux en oto-rhino-laryngologie. Le Dr Igor Anurin vit à Varsovie.

Il est actuellement chirurgien en chef au service ORL de l'hôpital Mazowiecki Bródnowski. Il est chef du service des urgences et chef de la spécialisation des internes. À la clinique Mea, il assure des consultations et pratique des interventions chirurgicales. Depuis plusieurs années, une grande partie de sa patientèle est russophone. La FESS (chirurgie endoscopique fonctionnelle des sinus) est une technique chirurgicale de drainage chirurgical mini-invasif des sinus paranasaux. Elle consiste à ouvrir les espaces nasaux étroits responsables du développement de la sinusite chronique et à les nettoyer mucociliairement. Les excroissances muqueuses, les polypes et les petites structures osseuses présentes dans les variantes anatomiques fonctionnellement défavorables sont retirés. L'objectif de la FESS est également d'ouvrir les sinus de la manière la plus atraumatique possible. L'intervention dure de 45 minutes à 2 heures, selon l'étendue de l'intervention.

2018 - Présent, Istanbul/Istanbul/Türkiye

HÔPITAL MEMORIAL BAHÇELİEVLER

Spécialiste des maladies des oreilles, du nez et de la gorge

2017 - 2018, Istanbul/Istanbul/Turquie

HÔPITAL FLORYA MEDICALPARK UNIVERSITÉ AYDIN ISTANBUL

Spécialiste des maladies des oreilles, du nez et de la gorge

2016 - 2017, Van/Van/Turquie

HÔPITAL RÉGIONAL DE FORMATION ET DE RECHERCHE VAN

Spécialiste des maladies des oreilles, du nez et de la gorge – Service obligatoire

2015 - 2016, Yozgat/Yozgat/Turquie

HÔPITAL D'ÉTAT DE YOZGAT

Spécialiste des maladies des oreilles, du nez et de la gorge – Service obligatoire

2009 - 2010, Siirt/Siirt/Turquie

HÔPITAL DU DISTRICT DE SİİRT BAYKAN

Spécialiste des maladies des oreilles, du nez et de la gorge – Service obligatoire

2021 - Aujourd'hui, Istanbul/Turquie

HÔPITAL MEMORIAL SIŞLI

Spécialiste des maladies des oreilles, du nez et de la gorge

2020 - 2021, Istanbul/Turquie

HÔPITAL DE SERVICE

Spécialiste des maladies des oreilles, du nez et de la gorge

2018 - 2018, /États-Unis

UNIVERSITÉ DE L'ARKANSAS POUR LES SCIENCES MÉDICALES

Observateur spécialiste des maladies des oreilles, du nez et de la gorge

2013 - 2019, Istanbul/Turquie

BAKIRKÖY DR. HÔPITAL DE FORMATION ET DE RECHERCHE SADI KONUK

Spécialiste des maladies des oreilles, du nez et de la gorge

Informations sur l'éducation :

Diplômé de l'école primaire Orgeneral Halil Sözer, Eskisehir – 2003
Diplômé du lycée anatolien Kılıçoğlu, Eskisehir -2007

Diplômé de la faculté de médecine de l'université de Marmara avec des cours entièrement en anglais, Istanbul, 2013

Stage à l'étranger :

Avril 2013 Stage d'un mois dans un service d'ORL à l'hôpital universitaire de Bâle, Bâle, Suisse

Expérience :

Stage sur l'apnée du sommeil au laboratoire de polisomnographie, section des maladies pulmonaires de l'hôpital Akademik, Istanbul. (2010-2011)

Expérience professionnelle dans la société Dr.Back Up liée à Medline, Istanbul. (entre juillet et octobre 2013)

Stage de travail dans une clinique d'urgence à l'hôpital municipal de Cankırı, Cankırı. (de novembre 2013 à janvier 2014)

Expérience professionnelle dans une clinique d'oto-rhino-laryngologie et de chirurgie de la tête et du cou à l'hôpital de recherche Bagcilar d'Istanbul (de juillet 2014 à 2018)

Expérience professionnelle dans une clinique d'oto-rhino-laryngologie, chirurgie de la tête et du cou à l'hôpital d'État Bahcelievler d'Istanbul (de septembre 2018 à 2020)

Expérience professionnelle dans une clinique d'oto-rhino-laryngologie, chirurgie de la tête et du cou à l'hôpital Florya Medical Park d'Istanbul (de janvier 2021 à novembre 2023)

Expérience professionnelle en tant qu'instructeur à la faculté de médecine de l'Université Aydın d'Istanbul (d'avril 2021 à décembre 2023)

Travaille actuellement dans sa clinique privée à Tesvikiye Mah. Terrace Fulya Center, Istanbul.

Travail principalement sur ;

Septorhinoplastie,

Rhinoplastie,

Tipplastie,

Rhinoplastie de révision,

Rhinoplastie ethnique

Rhinoplastie asiatique

Otoplastie.

Chirurgie de lifting des lèvres,

Bichectomie,

Implants du menton,

Septoplastie,

Septoplastie endoscopique,

Congrès:

2008, 2009, 2010 Masco ( Congrès des étudiants en médecine de Marmara )

18 avril 2013, Congrès international de chirurgie pédiatrique, Aarau, Bade, Suisse

37e Congrès national turc d'oto-rhino-laryngologie et de chirurgie de la tête et du cou - 2015

12e Congrès national turc de rhinologie-2016

8e Congrès national turc des chirurgiens ORL d'Istanbul - 2016

13e Congrès national turc de rhinologie-2017

14e Congrès national turc de rhinologie-2018

41e Congrès national turc d'oto-rhino-laryngologie et de chirurgie de la tête et du cou-2020

Revues et recherches internationales :

http://mmj.dergisi.org/pdf/pdf_MMJ_523.pdf Pg.33, présentation orale 28.

« Comparaison des taux de syndrome de Frey après parotidectomie superficielle et parotidectomie superficielle partielle pour adénome pléomorphe. »

PMID : 27391515

J Craniofac Surg. 2016 juill.;27(5):e469-71

« Le rapport neutrophiles sériques/lymphocytes peut-il être un biomarqueur prédictif pour aider à différencier l'otite moyenne chronique active de l'otite moyenne chronique inactive ? »

J Craniofac Surg.  

« Effets histopathologiques du ciment osseux sur le tissu cartilagineux »

J Craniofac Surg. Mai/juin 2019;30(3):936-939.

doi: 10.1097/SCS.0000000000005202.

« Maux naso-sinusiens unilatérales : une étude rétrospective »

North Clin Istanb. 12 avril 2018 ;5(2):139-143.

doi: 10.14744/nci.2017.57984. eCollection 2018.

« Effets des modifications répétées de la pression atmosphérique sur l’oreille interne. »

Aerosp Med Hum Perform. 1er juillet 2021;92(7):550-555.

doi:10.3357/AMHP.5732.2021. PMID: 34503628

« Association de la perte auditive conductive avec les changements structurels dans le

Orgue de Corti.

ORL J Otorhinolaryngol Relat Spec. 2021;83(4):272-279. est ce que je:

10.1159/000513871. Publication électronique du 30 mars 2021. PMID : 33784680

« Stadification de l'imagerie thoracique et prévalence du tabagisme actuel chez les patients hospitalisés

Patients atteints de la COVID-19 en Turquie.

ENT-Uptades. 2022; 12: 44-50

DOI : 10.5152/entupdates.2021.21065

Revues et recherches nationales :

http://mmj.dergisi.org/pdf/pdf_MMJ_523.pdf Pg.33, présentation orale 28.

« La fiabilité de l’approvisionnement en eau municipale d’Istanbul en termes de santé publique »

Recherches en cours :

Sérum vitamine D düzeyinin BPPV üzerine etkisi.

Cours de médecine suivis :

École de rhinoplastie à Eskisehir – juillet 2015

Problèmes des voies respiratoires chez l'enfant et chirurgie en direct - Avril 2015

Chirurgie endoscopique fonctionnelle des sinus – octobre 2015

Cours sur la chirurgie endoscopique fonctionnelle des sinus sur cadavre - Août 2016

Cours sur l'apnée obstructive du sommeil - octobre 2016

Cours de chirurgie plastique du visage - Octobre 2016

Cours de chirurgie plastique du visage, Sapanca, 2017

Cours de chirurgie de l'oreille moyenne sur cadavre - 2017

École de rhinoplastie - 2019

Cours de rhinoplastie tout-en-un - 2019

Cours de rhinoplastie tout-en-un - 2020

Cours de Botox et de remplissage - 2020

Langues étrangères :

Anglais (avancé)

Allemand (débutant)

Membres des communautés :

Turk Tabipler Birligi - Syndicat des médecins turcs

EAACI - Académie européenne d'allergie et d'immunologie clinique

Dr. Süleyman Hilmi Yilmaz, M.D., is an Assistant Professor in otorhinolaryngology. He specializes in nasal congestion, nasal deformity, polyposis, lacrimal gland obstructions, head and neck tumors, and thyroid cancer. He also performs advanced ENT surgeries, including endoscopic sinus surgery and septal correction.

He graduated from Kocaeli University Faculty of Medicine in 2006. He completed his residency at Istanbul Kartal Training and Research Hospital in 2013. Dr. Yilmaz has published many articles in both local and international journals. He is a member of the Turkish Otorhinolaryngology Head and Neck Surgery Association, the Istanbul ENT-BCC Specialists Association, and the Skull Base Association.

CURRICULUM VITAE

VOLKERT B. WREESMANN MD PhD

Consultant Otolaryngologist

Oncologic Head and Neck Surgeon

Thyroid and Parathyroid Surgeon

Facial Plastic Surgeon

Principal Positions

• Centro Medico Teknon, Barcelona, Spain

Chairman, Department of Otolaryngology-Head and Neck Surgery

July 1st 2024 – present

• Juaneda, Ciutadella Menorca, Spain

Consultant Otolaryngologist-Head and Neck Surgeon

January 2025 – present

• Avantmedic, Lleida, Spain

Consultant Otolaryngologist-Head and Neck Surgeon

July 1st 2024 – present

• Clinica Omega Zeta, Andorra

Consultant Otolaryngologist-Head and Neck Surgeon

March 1st 2022 – present

• University Hospitals Dorset NHS Foundation Trust

Consultant Otolaryngologist-Head and Neck Surgeon

August 1st 2021 – October 1st 2023

• Oxford University Hospitals NHS Foundation Trust

Honorary Consultant Otolaryngologist-Head and Neck Surgeon

May 1st 2021 – April 30th 2024

• Portsmouth Hospitals University NHS Trust, Portsmouth, UK

Consultant Otolaryngologist-Head and Neck Surgeon

July 18th 2016 – April 30th 2021

• Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK

Consultant Otolaryngologist-Head and Neck Surgeon

November 7th 2015 – May 31st 2016

• Heart of England NHS Trust, Birmingham, UK

Consultant Otolaryngologist-Head and Neck Surgeon

March 1st 2015 – October 31st 2015

• University Medical Center Utrecht, Netherlands

Consultant Otolaryngologist-Head and Neck Surgeon

November 1st 2013 – June 1st 2014

Memberships

• American Head and Neck Society – Member

Netherlands Academy of Otolaryngology - Member

Professional Licences

• United Kingdom

GMC Certification

Fully Registered Medical Practitioner with Specialist Registration with a License to Practice

Registered: 02/02/2015

GMC # 7499626

• United States of America

New York State Department of Health

New York State Education Department

Registered: July 2011

License# P80949

Physician

• Netherlands

Dutch Ministry of Health (BIG Registration)

BIG Registered: 22-06-2005

BIG #19063373601

Physician

Dutch Specialist Board (RGS)

RGS registered: 01-02-2011

RGS #1911979

Otolaryngology-Head and Neck Surgeon

• Spain

Collegi de Metges de Barcelona

COMB: 63638

• Andorra

Collegi de Metges d’Andorra

RPS: 03098

COMA: 876

Education

• Memorial Sloan-Kettering Cancer Center

Surgical Fellowship, Head and Neck Surgery

New York, New York, USA

August 1st 2011 - July 31st 2013

600 bed dedicated cancer center

Performed 1200 major oncologic head and neck resections in 2 years

• United States of America ECFMG Certification

United States Medical Licensing Examination (USMLE)

Certification: June 22nd, 2010

Scores: 

   Step I: 244/99 

   Step IIa-Clinical knowledge: 227/94

   Step IIb-Clinical Skills: PASSED

   Step III: 206/85

• Netherlands Cancer Institute

Surgical Fellowship, Head and Neck Surgery

Amsterdam, The Netherlands

February 1st 2011 - July 31st 2011

Specialized Head and Neck Cancer Surgery Department

200 bed hospital

• Amsterdam University Medical Center/Netherlands Cancer Institute

Residency Training, Otolaryngology-Head and Neck Surgery

Amsterdam, the Netherlands

February 1st 2006 – January 31st 2011

• University of Amsterdam School of Medicine

Medical Doctor (MD)

Amsterdam, the Netherlands

December 2002 - January 28th 2005

• University of Amsterdam

Doctor of Philosophy (PhD), Molecular Biology

Amsterdam, the Netherlands

Thesis title: Molecular-cytogenetic characterization of head and neck cancer

December 2nd, 2004

• Erasmus University School of Medicine

Doctoral Degree in Medicine

Rotterdam, the Netherlands

September 1994 - November 17th, 1998

Research Training

• Memorial Sloan-Kettering Cancer Center

Laboratory of Epithelial Cancer Biology, Head and Neck Service, Department of Surgery, New York, New York, USA

Research Fellowship in Molecular Oncology

Supervisors: Dr. Bhuvanesh Singh MD, PhD and Dr. Jatin P. Shah, MD, FACS

March 1st 1999 - September 30st 2002

• University of California San Francisco (UCSF)

Department of Otolaryngology-Head and Neck Surgery, San Francisco, California, USA

Post-doctoral Research Fellowship in Head and Neck Oncology

Supervisors: Dr. Steven Wang MD And Prof David Eisele MD

February 2005 - January 2006

Academic Activities

University of Amsterdam

Doctorate Examination Committee member

• September 17th, 2013 - PhD Candidate: Dr. I.J. Nixon (United Kingdom)
• October 17th 2014 - PhD Candidate: Dr. J. Pramana (Netherlands)
• November 17th 2015 - PhD candidate: Dr. H. van Monsjou (Netherlands)
• December 11th 2018 - PhD Candidate: Dr. Tihana Ibrahimpasic (United States)
• January 18th, 2021 - PhD Candidate: Dr. Laura Wang (Australia)
• June 2nd, 2021 - PhD Candidate: Dr. Caroline Verhagen (Netherlands)

Conference Faculty

• Advanced Laryngopharyngeal Cancer: Functional Preservation and Rehabilitation, Portsmouth, June 25th - 26th, 2020 (postponed due to COVID) - Chairman
• Functional Preservation and Rehabilitation after Treatment for Advanced Laryngeal Cancer, Portsmouth, March 14th - 15th, 2019 - Chairman
• Portsmouth Parathyroid Conference, Portsmouth, December 14th 2018 – Chairman

Editorial Roles

• European Journal of Surgical Oncology

Associate Editor

January 1st 2023 – present

• European Journal of Surgical Oncology

Guest Editor

March issue 2018, Volume 44, Issue 3, p275-378 - Special issue on thyroid cancer management

• Journal of Oral Pathology and Medicine

Guest Editor

November issue 2021, Volume 51, Issue 10 - Special issue on vascular malformations and tumors of the head and neck

• Scientific Journal Reviewer

Oral Oncology, European Journal of Surgical Oncology, Journal of Surgical Oncology, Head and Neck, International Journal of Cancer

• Scientific Project and Grant Reviewer

Netherlands: Dutch Cancer Society

France: Institute National du Cancer

Awards

• New York Head and Neck Society

Annual Meeting, New York, NY, March 2002

Title of study presented: “MUC1 is a target if 1q amplification and pertains a grave clinical prognosis in papillary thyroid cancer”

Invited Lectures

• European Society of Surgical Oncology meeting, Krakow, 2016
• Barcelona Society of Neurosurgery, Annual Meeting, Baqueira, Spain, February, 2017
• University of Edinburgh, Department of Otolaryngology Academic Conference, March 17th 2017
• Medilex: Performance of Medical Specialists, Zeist, Netherlands, November 9th 2017
• Medilex: Performance of Medical Specialists, Driebergen, Netherlands, October 11th 2017
• Wessex Head and Neck and Thyroid Network Education Day, May 3rd, 2017
• Portsmouth Parathyroid Conference, Portsmouth, UK, December 14th 2018
• Global Post-laryngectomy Rehabilitation Academy, Portsmouth, UK, March 14th 2019
• Health Care Quality Conference, Beverwijk, Netherlands, March 25th, 2019

Published Research Reports

• The growing precision of diagnostic pathways in thyroid nodule evaluation. 

Bekker J, Wreesmann VB. 

Eur J Surg Oncol. 2025 Jan;51(1):109374.

• Special issue: Management of vascular tumors and malformations of the head and neck. 

Oomen KPQ, Brennan PA, Wreesmann VB. 

J Oral Pathol Med. 2022 Nov;51(10):829.

• Angiosarcomas of the head and neck: Impact of large data analysis on clinical management.
•  
• Wreesmann VB, Oomen KP, Brennan PA.

J Oral Pathol Med. 2022 Nov;51(10):904-910.

• Current classification of vascular anomalies of the head and neck. 

Oomen KPQ, Wreesmann VB. 

J Oral Pathol Med. 2022 Nov;51(10):830-836.

• A novel classification of carotid body tumors.

Wreesmann VB, Nixon IJ. 

Eur. J. Surg. Oncol. May, 2021

• Management of the contralateral central neck in differentiated thyroid cancer: A contentious issue. 

Shaha AR, Tuttle RM, Wreesmann VB. 

Eur. J. Surg. Oncol. 2021 Apr;47(4):717-719.

• Improvement of oral cancer screening quality and reach: The promise of artificial intelligence.
•  
• Kar A, Wreesmann VB, Shwetha V, Thakur S, Rao VUS, Arakeri G, Brennan PA.

J Oral Pathol Med. 2020 Mar 11

• The risk-benefit ratio of chemoradiation treatment in head and neck squamous cell carcinoma: value of extranodal spread and margin status. 

Ammar M, Wreesmann VB. 

Journal of ENT Masterclass, Yearbook 2018, Volume 11, Nr. 1, December 1st, 2018

• Nasal obstruction secondary to an inverted midline supernumerary tooth. 

Jones L, Hilton JM, Heyman J, Viswanathan H, Wreesmann VB, Hayes SM. 

Ann R Coll Surg Engl. 2019 Jan;101(1)

• Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma. 

Verhagen CVM, Vossen DM, Borgmann K, Hageman F, Grénman R, Verwijs-Janssen M, Mout L, Kluin RJC, Nieuwland M, Severson TM, Velds A, Kerkhoven R, O'Connor MJ, van der Heijden M, van Velthuysen ML, Verheij M, Wreesmann VB, Wessels LFA, van den Brekel MWM, Vens C. 

Oncotarget. 2018 Apr 6;9(26):18198-18213.

• Complete nasal obstruction secondary to pacemaker insertion. 

Jones TL, Wreesmann VB, Nilssen E, Hilton J, Hayes SM. 

Ann R Coll Surg Engl. 2018 May;100(5)

• Optimization of the risk-benefit ratio of differentiated thyroid cancer treatment. 

Nasef HO, Nixon IJ, Wreesmann VB. Eur J Surg Oncol. 

2018 Mar;44(3):276-285. Review.

• The risk/benefit ratio of differentiated thyroid cancer treatment: Exploring treatment de-escalation. 

Wreesmann VB; on behalf of EJSO. 

Eur J Surg Oncol. 2018 Mar;44(3):275.

• Aggressive differentiated thyroid cancer. 

Janjua N, Wreesmann VB. 

Eur J Surg Oncol. 2018 Mar;44(3):367-377. Review.

• Role of extracapsular nodal spread and surgical margin status in defining high-risk head and neck squamous cell carcinoma and its treatment intensity. 

Wreesmann VB. 

International Journal of Head and Neck Surgery, April-June 2017; 8(2): 76-83.

• An International Multi-Institutional Validation of Age 55 Years as a Cutoff for Risk Stratification in the AJCC/UICC Staging System for Well-Differentiated Thyroid Cancer.              

Nixon IJ, Wang LY, Migliacci JC, Eskander A, Campbell MJ, Aniss A, Morris L, Vaisman F, Corbo R, Momesso D, Vaisman M, Carvalho A, Learoyd D, Leslie WD, Nason RW, Kuk D, Wreesmann V, Morris L, Palmer FL, Ganly I, Patel SG, Singh B, Tuttle RM, Shaha AR, Gönen M, Pathak KA, Shen WT, Sywak M, Kowalski L, Freeman J, Perrier N, Shah JP. 

Thyroid. 2016 Mar;26(3):373-80.

• Influence of extracapsular nodal spread extent on prognosis of oral squamous cell carcinoma. 
•  
• Wreesmann VB, Katabi N, Palmer FL, Montero PH, Migliacci JC, Gönen M, Carlson D, Ganly I, Shah JP, Ghossein R, Patel SG.

Head Neck. 2016 Apr;38 Suppl 1:E1192-9.

• Defining a Valid Age Cutoff in Staging of Well-Differentiated Thyroid Cancer. 

Nixon IJ, Kuk D, Wreesmann V, Morris L, Palmer FL, Ganly I, Patel SG, Singh B, Tuttle RM, Shaha AR, Gönen M, Shah JP. 

Ann Surg Oncol. 2015 Jul 28.

• Prognostic value of vascular invasion in well-differentiated papillary thyroid carcinoma.
•  
• Wreesmann VB, Nixon IJ, Rivera M, Katabi N, Palmer F, Ganly I, Shaha AR, Tuttle RM, Shah JP, Patel SG, Ghossein RA.

Thyroid. 2015 May;25(5):503-8.

• Head and neck squamous cell carcinoma in young patients.

van Monsjou HS, Wreesmann VB, van den Brekel MW, Balm AJ. 

Oral Oncol. 2013 Dec;49(12):1097-102.

• Oral and oropharyngeal squamous cell carcinomas in young patients: The Netherlands Cancer Institute experience. 

van Monsjou HS, M Lopez-Yurda, M. Hauptmann, Balm AJ, van den Brekel MM, Wreesmann VB. 

Head Neck. 2013 Jan;35(1):94-102.

• Oropharyngeal squamous cell carcinoma: a unique disease on the rise?

van Monsjou HS, Balm AJ, van den Brekel MM, Wreesmann VB. 

Oral Oncol. 2010 Nov;46(11):780-5.

• Closure of tracheoesophageal fistula with prefabricated revascularized bilaminar radial forearm free flap.

Wreesmann VB, Smeele LE, Hilgers FJ, Lohuis PJ. 

Head Neck. 2009 Jun;31(6):838-42.

• Clinical impact of molecular analysis on thyroid cancer management.

Wreesmann VB, Singh B. 

Surg Oncol Clin N Am. 2008 Jan;17(1):1-35.

Genetic abnormalities associated with chemoradiation resistance of head and neck squamous cell carcinoma. 

van den Broek GB, Wreesmann VB, van den Brekel MW, Rasch CR, Balm AJ, Rao PH. 

Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4386-91.

• Association of CD44 V3-containing isoforms with tumor cell growth, migration, matrix metalloproteinase expression, and lymph node metastasis in head and neck cancer.

Wang SJ, Wreesmann VB, Bourguignon LY. 

Head Neck. 2007 Jun;29(6):550-8.

• Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma.
•  
• Wreesmann VB, Estilo C, Eisele DW, Singh B, Wang SJ.

ORL J Otorhinolaryngol Relat Spec. 2007;69(4):218-25. Epub 2007 Apr 4.

• Patterns of expression of cell cycle/apoptosis genes along the spectrum of thyroid carcinoma progression.
•  
• Saltman B, Singh B, Hedvat CV, Wreesmann VB, Ghossein R.
•  
• Surgery. 2006 Dec;140(6):899-905; discussion 905-6.

• Repetitive endoscopic sinus surgery failure: a role for radical surgery?

Videler WJ, Wreesmann VB, van der Meulen FW, Knegt PP, Fokkens WJ. 

Otolaryngol Head Neck Surg. 2006 Apr;134(4):586-91.

• MUC1 plays a role in tumor maintenance in aggressive thyroid carcinomas.
•  
• Patel KN, Maghami E, Wreesmann VB, Shaha AR, Shah JP, Ghossein R, Singh B.
•  
• Surgery. 2005 Dec;138(6):994-1001; discussion 1001-2.

• Chromosomal aberrations in squamous cell carcinomas of the upper aerodigestive tract: biologic insights and clinical opportunities.

Wreesmann VB, Singh B. 

J Oral Pathol Med. 2005 Sep;34(8):449-59. Review.

• Molecular profiling of tumor progression in head and neck cancer.
•  
• Belbin TJ, Singh B, Smith RV, Socci ND, Wreesmann VB, Sanchez-Carbayo M, Masterson J, Patel S, Cordon-Cardo C, Prystowsky MB, Childs G.
•  
• Arch Otolaryngol Head Neck Surg. 2005 Jan;131(1):10-8.

• Identification of novel prognosticators of outcome in squamous cell carcinoma of the head and neck.

Wreesmann VB, Shi W, Thaler HT, Poluri A, Kraus DH, Pfister D, Shaha AR, Shah JP, Rao PH, Singh B. 

J Clin Oncol. 2004 Oct 1;22(19):3965-72.

• Follicular variant of papillary thyroid carcinoma: genome-wide appraisal of a controversial entity.

Wreesmann VB, Ghossein RA, Hezel M, Banerjee D, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B. 

Genes Chromosomes Cancer. 2004 Aug;40(4):355-64.

• Genome-wide profiling of papillary thyroid cancer identifies MUC1 as an independent prognostic marker.

Wreesmann VB, Sieczka EM, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Patel KN, Tallini G, Prystowsky M, Shaha AR, Kraus D, Shah JP, Rao PH, Ghossein R, Singh B. 

Cancer Res. 2004 Jun 1;64(11):3780-9.

• Genetic abnormalities associated with nodal metastasis in head and neck cancer.

Wreesmann VB, Wang D, Goberdhan A, Prasad M, Ngai I, Schnaser EA, Sacks PG, Singh B. 

Head Neck. 2004 Jan;26(1):10-5.

• Human papillomavirus DNA and p53 polymorphisms in squamous cell carcinomas from Fanconi anemia patients.
•  
• Kutler DI, Wreesmann VB, Goberdhan A, Ben-Porat L, Satagopan J, Ngai I, Huvos AG, Giampietro P, Levran O, Pujara K, Diotti R, Carlson D, Huryn LA, Auerbach AD, Singh B.
•  
• J Natl Cancer Inst. 2003 Nov 19;95(22):1718-21.

• Chromosomal aberrations in patients with head and neck squamous cell carcinoma do not vary based on severity of tobacco/alcohol exposure.

Singh B, Wreesmann VB, Pfister D, Poluri A, Shaha AR, Kraus D, Shah JP, Rao PH. 

BMC Genet. 2002 Nov 14;3:22. Epub 2002 Nov 14.

• Genome-wide appraisal of thyroid cancer progression.
•  
• Wreesmann VB, Ghossein RA, Patel SG, Harris CP, Schnaser EA, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B.
•  
• Am J Pathol. 2002 Nov;161(5):1549-56.

• Refractory chronic sinusitis: evaluation of symptom improvement after Denker’s procedure.
•  
• Wreesmann VB, Fokkens WJ, Knegt PP.
•  
• Otolaryngol Head Neck Surg. 2001 Nov;125(5):495-500.

• Inflammatory pseudotumour (inflammatory myofibroblastic tumour) of the pancreas: a report of six cases associated with obliterative phlebitis.
•  
• Wreesmann V, van Eijck CH, Naus DC, van Velthuysen ML, Jeekel J, Mooi WJ.
•  
• Histopathology. 2001 Feb;38(2):105-10.

• Screening for genetic aberrations in papillary thyroid cancer by using comparative genomic hybridization.
•  
• Singh B, Lim D, Cigudosa JC, Ghossein R, Shaha AR, Poluri A, Wreesmann VB, Tuttle M, Shah JP, Rao PH.
•  
• Surgery. 2000 Dec;128(6):888-93;discussion 893-4.

Abstracts (Presentations at scientific meetings):

• Genome-wide screening for genetic prognostic factors in papillary thyroid carcinoma.
•  
• Wreesmann VB, Ghossein RA, Poluri A, Shaha AR, Tuttle RM, Shah JP Rao PH, Singh B.

Fifth International Conference on Head and Neck Cancer San Francisco, CA, July 2000.

• Hierarchical Clustering (HC): a Novel Approach to Evaluating the Prognostic Value of Laboratory Parameters in Patients (Pts) Undergoing Chemoradiation Treatment (CRT) for Advanced Laryngopharyngeal Carcinoma (LPC). 

Singh B, Pfister D, Wreesmann VB, Li R, Gogineni S, Bosl G, Hoffman RH, Shah JP, Rao PH. 

37th Annual Meeting of the American Society of Clinical Oncology; New Orleans LA, May 2001.

• Gain of 1q is unique to the tall cell variant of papillary thyroid cancer.

Wreesmann VB, Ghossein RA, Tuttle RM, Shaha AR, Robbins R, Shah JP, Rao PH, Singh B. 

73rd annual meeting of the American Thyroid Association, Washington D.C. November 2001.

• MUC1 is a target of 1q amplification and pertains a grave clinical prognosis in papillary thyroid cancer. 

Wreesmann VB, Sieczka E, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Shah JP, Rao PH, Ghossein RG, Singh B. 

Annual Meeting of the New York Head and Neck Society, New York, NY, March 2002.

• Genome wide screening identified gains and losses as independent prognostic variables in patients with head and neck squamous cell carcinoma (HNSCC). 

Singh B, Wreesmann VB, Thaler HT, Shi W, Shah JP, Shaha AR, Kraus DH, Boyle JO, Pfister D, Rao PH. 

38th Annual Meeting of the American Society of Clinical Oncology; Orlando, Fl May 2002.

• p53 inactivation by human papillomavirus (HPV) in Fanconi anemia associated squamous cell carcinoma. 

Kutler DI, Goberdhan A, Wreesmann VB, Giampietro PF, Auerbach AD, Singh B. 

The Sixth Research Workshop on the Biology, Prevention, and Treatment of Head and Neck Cancer; Washington D.C.; October 2002.

• Identification of novel prognostic factors in head and neck squamous cell carcinoma. 
•  
• Wreesmann VB, Shi W, Thaler HT, Shah JP, Shaha AR, Kraus DH, Boyle JO, Pfister D, Rao PH, Singh B. 

7th symposion on Research in Head and Neck Cancer; Dusseldorf, Germany, September 4-6 2003.

• Molecular profiling of aggressive papillary thyroid cancer: prognostic significance of MUC1 alterations. 

Wreesmann VB, Sieczka E, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Patel KN, Tallini G, Prystowsky M, Shaha AR, Kraus D, Shah JP, Rao PH, Ghossein RA, Singh B. 

7th symposion on Research in Head and Neck Cancer; Dusseldorf, Germany, September 4-6 2003.

• Chromosomal aberrations in Fanconi anemia-associated squamous cell carcinomas differ from sporadic squamous cell carcinomas from the general population. 

Kutler DI, Rao PH, Wreesmann VB, Goberdhan A, Ngai I, Huvos AG, Giampietro PF, Levran O, Pujara K, Diotti R, Auerbach AD, Singh B. 

15th annual Fanconi Anemia Research Fund scientific symposium, Houston TX, Oct 2003.

• Molecular classification of Fanconi anemia(FA)-associated head and neck squamous cell carcinoma (HNSCC) using oligonucleotide microarrays. 

Kutler DI, Ganly I, Wreesmann VB, Goberdhan A, Ngai I, Huvos AG, Giampietro PF, Levran O, Pujara K, Diotti R, Auerbach AD, Singh B. 

15th annual Fanconi Anemia Research Fund scientific symposium, Houston TX, Oct 2003.

•  
• Genotyping follicular cell-derived thyroid neoplasia: a CGH study of 150 cases.

Wreesmann VB, Ghossein RA, Socci N, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B. 

Sixth International Conference on Head and Neck Cancer, Washington DC, August 2004.

• Downregulation of Fanconi anemia genes in sporadic squamous cell carcinomas of the head and neck. 

Wreesmann VB, Estilo C, Eisele DW, Singh B, Wang SJ. 

208th meeting of the Netherlands Society of Otolaryngology-Head and Neck Surgery, Utrecht, April 7th 2006.

• Extracapsular nodal spread does not predict outcome in clinically node negative oral cavity squamous cell carcinoma. 

Wreesmann VB, Ghossein RA, Carlson D, Ganly I, Palmer F, Montero P, Shah JP, Patel SG. 

AHNS 2013 Annual Meeting, April 10 & 11, 2013, Orlando Florida.

• Minor (<2mm) extracapsular spread is not an adverse predictor of outcome in metastatic squamous cell carcinoma of the oral cavity. 

Wreesmann VB, Ghossein RA, Carlson D, Ganly I, Palmer F, Montero P, Shah JP, Patel SG. 

Presented at the AHNS 2014 Annual Meeting, July 2014, New York, New York.

Books, Chapters:

• Molecular Biology as applied to Head and Neck Oncology

Wreesmann VB, Singh B.

Stell and Maran's Textbook of Head and Neck Surgery and Oncology

Fifth Edition

Chapter, edited by John Watkinson and Ralph Gilbert

• Molecular-Cytogenetic Characterization of Head and Neck Cancer: Identification of molecular prognostic factors and targets of therapy

Wreesmann VB, Singh B.

Book, Amsterdam 2004

Reviewed in: Head and Neck: Volume 29, Issue 1, pages 82–83, January 2007

• Open Conservation Surgery for Laryngeal Cancer

Wreesmann VB, Ganly I

Scott-Brown's Otorhinolaryngology and Head and Neck Surgery, Eighth Edition

Chapter 27

CRC Press, Taylor-Francis Group, June 12th, 2018

• Molecular Oncology

Wreesmann V.B.

Self-Assessment in Head and Neck Surgery and Oncology, First Edition

Chapter 21

Elsevier 2014

Research grants:

Netherlands Cancer Institute “Startgeld” Grant 2008

Project: Fanconi anemia in head and neck cancer

Principal investigators: Wreesmann VB, van den Brekel MW, Balm AJM, Vens C.

Amount granted: 300.000 euro

Dr. Ismail Onder Uysal is a specialist in plastic surgery and ENT with over 26 years of experience. He has performed around 2,500 procedures. He is known worldwide for his skills in rhinoplasty, including open and closed techniques and revision surgeries.

Dr. Uysal graduated from Cumhuriyet University in 1999. He has worked as a lecturer in academic medicine and has published in international medical journals. Many patients from different countries seek his advanced surgical care.

Dr. Jordi Coromina Isern is a respected otolaryngologist with over 30 years of experience. He specializes in treating ENT diseases. He is skilled in advanced surgeries, including cochlear implants, septoplasty, tonsillectomy, tympanoplasty, and cleft lip or palate repair.

Dr. Coromina is known for introducing laser and Da Vinci robotic surgeries in ENT care. He has received the César Bertrán Award from the Spanish Society of Otolaryngology. He also received an award from the Catalan Society of Pulmonology for his clinical achievements.

He is a member of several leading medical societies. He completed his medical training with honors and gained international experience at institutions such as Mayo Clinic and Boston Children's Hospital.

Op. Dr. Yasemin Ongun is a specialist in Ear, Nose, and Throat (ENT) and Head & Neck Surgery. She graduated from Kocaeli University Faculty of Medicine in 2005. In 2008, she completed advanced training in Otology-Neurotology, Audiology, and Head and Neck Surgery at Hacettepe University.

Dr. Ongun has worked in both public and private healthcare settings. She served at Şanlıurfa Mehmet Akif İnan Training and Research Hospital and held the position of deputy chief physician in private hospitals. She has performed many surgeries, with a focus on rhinoplasty, endoscopic sinus surgery, pediatric ENT procedures, otoplasty, and hearing-related operations.

Le médecin est spécialisé dans le traitement chirurgical des maladies de l'oreille, de la gorge et du nez :

• Nez : Chirurgie de la cloison nasale, chirurgie des cornets, toutes chirurgies des sinus (chirurgies endoscopiques des sinus – FESS), ablation des lésions nasales et biopsie, réduction des fractures nasales.
• Gorge : Amygdalectomie, ablation de nodules de la gorge, biopsies de la gorge, chirurgies pour l'apnée du sommeil/ronflement (radiochirurgie).
• Oreille : Paracentèse, chirurgies de l'oreille (par exemple, ablation de lésions de l'oreille, biopsies).
• Cou : Ablation de kystes et de tumeurs du cou, biopsies de lésions du cou.
• Larynx : Toutes les chirurgies du larynx (microchirurgie, directoscopie, etc.), trachéotomie (création d'une ouverture dans la trachée).
• Procédures d'urgence : réduction d'une fracture nasale, réduction d'une fracture de la cloison nasale, prise en charge des saignements nasaux, tamponnement nasal en cas d'hémorragie, cautérisation des vaisseaux en cas de saignement nasal, incision d'abcès périamygdaliens, d'abcès cervicaux, de phlegmons cervicaux, de biopsies de tumeurs cervicales ou de ganglions lymphatiques, trachéotomie (création d'une ouverture dans la trachée). Retrait de corps étrangers de l'oreille, de la gorge ou du nez.
• Procédures ambulatoires : y compris chez les enfants, telles que la libération du frein de langue, etc.
• Procédures d'oto-rhino-laryngologie palliative .

Éducation

• Diplômé du programme d'études doctorales au Centre médical de formation postuniversitaire (CMKP) - Varsovie.
• Diplôme de Spécialiste en Oto-Rhino-Laryngologie (Varsovie).
• Études de troisième cycle, Institut Paul VI. Certificat de l'Université Creighton (Omaha, Nebraska, USA).
• Stage de troisième cycle à l'Université de médecine de Varsovie.
• Diplômé avec mention de la Faculté de médecine de l'Université médicale d'État de Zaporozhye (Ukraine).

Expérience professionnelle

• Spécialiste adjoint principal à la clinique d'oto-rhino-laryngologie, CMKP, hôpital Brodno, Varsovie.
• Membre du personnel de longue date et chef des services d'urgence ORL à Varsovie.
• Spécialisation en oto-rhino-laryngologie au département d'oto-rhino-laryngologie, hôpital Bielanski, Varsovie (2004-2005).
• Stage de troisième cycle à l'Université de médecine de Varsovie.

Dr Palapong Chayangsu, MD

Expert en chirurgie plastique et reconstructrice du visage

À propos du Dr Palapong Chayangsu

Le Dr Palapong Chayangsu est un chirurgien plasticien facial certifié, fort de 20 ans d'expérience en chirurgie esthétique et reconstructive. Certifié par l'International Board of Facial Plastic and Reconstructive Surgery (IBCFPRS), il est spécialisé en lifting, rhinoplastie et chirurgie des paupières. Reconnu pour sa précision et son approche centrée sur le patient, le Dr Chayangsu s'engage à offrir des résultats naturels et durables.

Expertise clé

• - Chirurgie de lifting du visage et du cou
• - Rhinoplastie (chirurgie du nez)
• - Blépharoplastie (chirurgie des paupières)

Éducation et certifications

• - Docteur en médecine (MD)
• - Certification du Conseil en oto-rhino-laryngologie – chirurgie de la tête et du cou
• - Certification internationale en chirurgie plastique et reconstructive du visage (IBCFPRS)

Expérience professionnelle

• - 20 ans en chirurgie plastique et reconstructrice du visage
• - Expertise en techniques avancées de rajeunissement du visage
• - Axé sur l'obtention de résultats naturels, équilibrés et durables