Mehmet Alpay Cal

Specialization and Surgical Focus

Dr. Cal treats various conditions affecting the brain and nervous system. His practice includes treating brain tumors, cerebral aneurysms, and arteriovenous malformations. He also addresses congenital issues such as craniostenosis and Chiari malformations.

The doctor performs several procedures:

• Deep brain stimulation (DBS) surgery – a procedure that uses implanted electrodes to treat movement disorders
• CyberKnife and Gamma Knife radiosurgery – non-invasive radiation treatments for tumors and lesions
• Surgical removal of brain tumors and cysts
• Scoliosis and spinal stenosis surgery
• Spinal cord stimulator (SCS) implantation – a device that sends electrical signals to the spinal cord to block pain
• Baclofen pump surgery for spasticity – an implanted device that delivers muscle relaxants directly to the spinal fluid
• Neurorrhaphy for peripheral nerve repair – a microsurgical technique to reconnect damaged nerves

Academic Research and Publications

Dr. Cal investigates laboratory markers and drug interactions in neurosurgery. His research covers cervical corpectomy techniques and analgesia for spine operations. He has authored multiple studies in international medical journals and examines antiepileptic drugs for brain tumor patients.

Selected Publications

• "Impact of subventricular zone interaction on clinical outcomes in patients with intracerebral hematoma," 2024
• "A Single-center Study Comparing Volumetric and Morphometric Measurements of Chiari Malformation," 2024
• "Rapid Recurrence of Glioblastoma After 12 Days Despite Gross Total Resection," 2024
• "The relationship between vertebral compression rates and systemic inflammatory scores," 2024
• "Retrospective Evaluation of the Effect of Surgery and CyberKnife on Recurrence and Neurological Deficits," 2023
• "The use of vancomycin powder in the compound depressed skull fractures," 2023
• "A rare case report: Cervical subcutaneous and mediastinal emphysema due to mastoid fracture," 2020
• "Neuroprotective effect of ziprasidone: Preliminary results compared to haloperidol," 2014
• "Bilateral epidural hematoma in a patient with Human immunodeficiency virus infection," 2013
• "Coexistence of spinal lipoma, ependymal cyst and dermoid cyst in neighboring localizations," 2013
• "Pneumorrhachis associated with bronchial asthma and subcutaneous emphysema," 2011
• "Correlation between leptin and pro-inflammatory cytokines in cortical contusion injury model," 2011

Work Experience

• Liv Hospital Ulus
• Sisli Kolan Hospital
• Prof. Dr. Cemil Taşcıoğlu City Hospital
• Ardahan State Hospital

Education and Training

• Istanbul University, Faculty of Medicine – Medical Degree
• Istanbul Okmeydani Training and Research Hospital – Residency

Professional Memberships

• Turkish Neurosurgery Association
• Istanbul Medical Chamber